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Reaction Kinetics

Reaction kinetics is the study of how fast chemical reactions go and what controls their speed. For the MCAT you should be able to define rate, write and interpret rate laws, determine reaction order and the rate constant, apply the Arrhenius equation and activation energy, use collision theory and reaction-coordinate diagrams, identify the rate-determining step of a mechanism, and explain how catalysts work.

MCAT high-yield topics. Rate laws, reaction order and the rate constant; the Arrhenius equation and activation energy; collision theory; reaction-coordinate (energy) diagrams; the rate-determining step; and catalysts. Determining order from initial-rate data and reading energy diagrams are the most common item types.

Chemical Kinetics

Chemical kinetics is the branch of chemistry that deals with the rate of a reaction and the mechanism by which it proceeds. Rate measures how fast reactants are consumed (or products formed) per unit time:

Rate = −Δ[Reactant] / Δt = +Δ[Product] / Δt

Units of rate: mol L−1 s−1. For aA + bB → cC + dD, rate = −(1/a) d[A]/dt = −(1/b) d[B]/dt = (1/c) d[C]/dt = (1/d) d[D]/dt.

Rate law (rate equation)

For a reaction aA + bB → products, the experimental rate law has the form:

Rate = k [A]m [B]n

where m and n are determined experimentally (not from the balanced equation), k is the rate constant, and m + n is the overall order.

Rate Constant

The rate constant k (also called specific rate constant) is the proportionality constant in the rate law. It is numerically equal to the rate when all reactant concentrations are 1 mol L−1.

Order of Reaction

The order with respect to a reactant is the power to which its concentration is raised in the experimentally determined rate law. The overall order is the sum of these powers.

Order vs molecularity

Integrated rate laws and half-lives

Order of reaction — rate law, integrated form, half-life, units of k
OrderRate lawIntegrated formHalf-life t½Units of kConcentration vs time graph
Zerorate = k[A] = [A]0 − kt[A]0 / (2k)mol L−1 s−1Linear decrease
Firstrate = k[A]ln[A] = ln[A]0 − kt0.693 / k (constant!)s−1Exponential decay
Secondrate = k[A]21/[A] = 1/[A]0 + kt1 / (k[A]0)L mol−1 s−1Slower decay than 1st order

Zero-order half-life depends on [A]0; first-order half-life is independent of [A]0 (key MCQ point); second-order half-life is inversely proportional to [A]0.

Pseudo-first-order reactions

If one reactant is in such large excess that its concentration is essentially constant, the reaction's apparent kinetic order drops by one. Acid-catalysed hydrolysis of an ester in dilute aqueous solution looks first-order in ester even though water is also a reactant, because [H2O] is virtually constant.

Collision Theory

Collision theory explains rate at the molecular level: molecules must collide to react, but only a fraction of collisions are effective. An effective collision requires (1) sufficient energy—at least the activation energy Ea—and (2) correct orientation of the colliding species. Rate ∝ (collision frequency) × (fraction with E ≥ Ea) × (orientation factor); these three factors map onto the Arrhenius terms A and e−Ea/RT.

Anything that raises collision frequency (higher concentration/pressure, larger surface area) or the fraction of sufficiently energetic collisions (higher temperature, lower Ea via a catalyst) increases the rate.

Activation Energy and Reaction-Coordinate Diagrams

The activation energy Ea is the minimum energy that colliding molecules must possess (above their average) for a successful reaction. It is the height of the energy barrier between reactants and products on a reaction-coordinate (potential-energy) diagram. The peak of that barrier is the transition state (activated complex)—a high-energy, non-isolable arrangement.

Reading the diagram: Ea,forward is measured from the reactants to the peak; Ea,reverse from the products to the peak; and ΔHrxn = Ea,forward − Ea,reverse (the energy gap between reactants and products). If products lie below reactants the reaction is exothermic (ΔH < 0); if above, endothermic. A multi-step mechanism shows one hump per step, with an intermediate sitting in the valley between humps.

Arrhenius equation

The temperature dependence of the rate constant is given by Arrhenius:

k = A · e−Ea/RT

Catalysts and Ea

A catalyst provides an alternative pathway with a lower activation energy. It speeds up forward and reverse reactions equally, so equilibrium position is unaffected; only the speed at which equilibrium is reached changes. A catalyst is recovered chemically unchanged at the end of the reaction. Catalysts lower Ea but never change ΔH, ΔG, or K.

Reaction Mechanism and Rate-Determining Step

Most reactions proceed through a series of elementary steps (a mechanism), not in a single collision. The slowest step is the rate-determining step (RDS); it acts as a bottleneck and dictates the overall rate law.

Factors Affecting Rate of Reaction

Common trap. The order of a reaction cannot be predicted from the balanced equation. For 2NO + O2 → 2NO2, the experimentally measured rate law is rate = k[NO]2[O2] — here it happens to match, but for many reactions it will not. Always quote the experimental order.
Memory aid. "First-order half-life is concentration-independent." t½ = 0.693 / k means radioactive decay (and many drug eliminations) take the same fixed time to halve, regardless of how much you started with.

Worked MCQs

Six MCQs that capture the high-yield testing patterns for this chapter. Read the explanation even when you get the answer right — it's where the deeper concept lives.

Q1. Which of the following is true about a catalyst?

  • It increases the activation energy of the reaction
  • It shifts the equilibrium towards products
  • It provides an alternative pathway with lower activation energy
  • It is consumed during the reaction

A catalyst lowers Ea by offering an alternative path. It speeds up both forward and reverse reactions equally, so the equilibrium position is unchanged, and it is recovered chemically unchanged at the end.

Q2. The half-life of a first-order reaction is:

  • Directly proportional to [A]0
  • Inversely proportional to [A]0
  • Independent of [A]0
  • Equal to 1 / k

For first-order kinetics, t½ = 0.693 / k — it depends only on k (and therefore on temperature/catalyst), not on the starting concentration. This is why radioactive decay has a fixed half-life.

Q3. For a reaction with rate law rate = k[A]2[B], the overall order is:

  • 1
  • 2
  • 3
  • 0

Overall order is the sum of the powers in the experimentally determined rate law. Here 2 + 1 = 3, so the reaction is third order overall (second order in A and first order in B).

Q4. Increasing the temperature of a reaction by 10 °C usually:

  • Has no effect on the rate
  • Halves the rate
  • Approximately doubles the rate
  • Decreases the activation energy

A 10 °C rise typically doubles the rate because a much larger fraction of molecules now have energy above Ea (Maxwell–Boltzmann distribution shifts right). Ea itself is unchanged — only k changes (Arrhenius).

Q5. The units of the rate constant for a first-order reaction are:

  • mol L−1 s−1
  • s−1
  • L mol−1 s−1
  • L2 mol−2 s−1

For first order, rate = k[A]. Rate has units mol L−1 s−1 and [A] has mol L−1, so k has units of s−1. (Zero order: mol L−1 s−1; second order: L mol−1 s−1.)

Q6. For A + B → products, doubling [A] doubles the rate; doubling [B] quadruples the rate. The rate law is:

  • rate = k[A][B]
  • rate = k[A]2[B]
  • rate = k[A][B]2
  • rate = k[A]2[B]2

Order is found from initial-rate data. Doubling [A] ×2 the rate → first order in A (21 = 2). Doubling [B] ×4 the rate → second order in B (22 = 4). So rate = k[A][B]2, third order overall. Orders come from the data, never from the coefficients.

Quick Recap

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